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F7H
Products Details
Product Description
– F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD)[1].
Web ID
– HY-156095
Shipping
– Room temperature
Molecular Formula
– C24H18FN3O2S2
References
– [1]Li C, et al. Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J Med Chem. 2023 Sep 14;66(17):11855-11868.. .
CAS Number
– 897109-93-2
Molecular Weight
– 463.55
SMILES
– O=C(C1=CC=C(C=C1)F)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Wnt
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
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