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F15845

Products Details

Product Description

– F 15845 is a highly effective persistent sodium current blocker. F 15845 also is a cardioprotective agent, has anti-ischemic activity and exerts short- and long-term cardioprotection after myocardial infarction. F 15845 can be used for the research of myocardium functional impairment[1].

Web ID

– HY-19463A

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C20H25NO2S2

References

Р[1]Bruno Vi̩, et al. 3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine bromhydrate (F 15845) prevents ischemia-induced heart remodeling by reduction of the intracellular Na+ overload. J Pharmacol Exp Ther. 2009 Sep;330(3):696-703.

CAS Number

– 470454-73-0

Molecular Weight

– 375.55

SMILES

– COC(C=CC=C1)=C1SC[C@@H](C)CN[C@@H]2COC3=CC=CC=C3SC2

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Sodium Channel

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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