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Excisanin A
Price range: 1,568 CAD through 7,680 CAD
Products Details
Product Description
– ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatment of breast cancer. Excisanin A shows comparable inhibitory effects on the LPS-induced production of NO and PGE2, and activation of NF-kappaB without affecting cell viability.Excisanin A induces apoptosis in colon cancer cell line SW620 as determined by Annexin V staining, the cleavage of caspase-3 and the proteolytic degradation of poly (ADP-ribose) polymerase (PARP).
Web ID
– TN4046
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H30O5
CAS Number
– 78536-37-5
Molecular Weight
– C20H30O5
SMILES
– CC1(C)CC[C@H](O)[C@@]2(C)[C@@H]3C[C@H](O)[C@@H]4[C@@H](O)[C@@]3([C@H](O)C[C@H]12)C(=O)C4=C
Pathway
– Angiogenesis|||Apoptosis|||MAPK|||GPCR/G Protein|||Cytoskeletal Signaling|||Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||NF-κB|||Immunology/Inflammation|||DNA Damage/DNA Repair|||Stem Cells|||Tyrosine Kinase/Adaptors|||Proteases/Proteasome
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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