Download Files:
Eupalinolide K
SKU
HY-N2240-Get quote
Category Natural Products
Tags Cancer, JAK/STAT Signaling;Stem Cell/Wnt, STAT
Products Details
Product Description
– Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1].
Web ID
– HY-N2240
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H26O6
References
– [1]Yang B, , et al. Precise discovery of a STAT3 inhibitor from <i>Eupatorium lindleyanum</i> and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485.
CAS Number
– 108657-10-9
Molecular Weight
– 362.42
SMILES
– O=C(/C(C)=C/CO)O[C@H](C/C(C)=CC[C@H](O)/C(C)=C1)[C@](C2=C)([H])[C@]1([H])OC2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– STAT
Isoform
– STAT3
Pathway
– JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.