Products Details

Product Description

– Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1].

Web ID

– HY-N2240

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C20H26O6

References

– [1]Yang B, , et al. Precise discovery of a STAT3 inhibitor from <i>Eupatorium lindleyanum</i> and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485.

CAS Number

– 108657-10-9

Molecular Weight

– 362.42

SMILES

– O=C(/C(C)=C/CO)O[C@H](C/C(C)=CC[C@H](O)/C(C)=C1)[C@](C2=C)([H])[C@]1([H])OC2=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– STAT

Isoform

– STAT3

Pathway

– JAK/STAT Signaling;Stem Cell/Wnt

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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