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Product Description
– Estrogen receptor antagonist 5 is a potent antagonist of Estrogen receptor. The estrogen receptor is a ligand-activated transcriptional regulatory protein that mediates induction of a variety of biological effects through its interaction with endogenous estrogens. Estrogen receptor antagonist 5 has the potential for the research of metastatic disease (extracted from patent WO2017174757A1, compound 165)[1].
Web ID
– HY-144204
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C25H31F3N2O3
References
– [1]Sharada Labadie, et al. Tetrahydroisoquinoline estrogen receptor modulators and uses thereof. Patent WO2017174757A1.
CAS Number
– 2136600-69-4
Molecular Weight
– 464.52
SMILES
– OCC(F)(F)CN1[C@@H](C2=CC=C(C=C2)OCCN3CC(C3)CF)C4=CC=C(O)C=C4C[C@@H]1C
Clinical Information
– No Development Reported
Research Area
– Cancer; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
