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Product Description
– Erythromycin aspartate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin aspartate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin aspartate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].
Web ID
– HY-B0220C
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C41H74N2O17
References
– [1]Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89.|[2]Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec. 100(3):185-91.|[3]Hamada K, et al. Antitumor effect of erythromycin in mice. Chemotherapy. 1995 Jan-Feb. 41(1):59-69. |[4]Katayama Y, et al. Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. Brain Res. 2014 Nov 7. 1588:159-67.
CAS Number
– 30010-41-4
Molecular Weight
– 867.03
SMILES
– C[C@@H]([C@@H]([C@H](C(O[C@@H]([C@@](O)1C)CC)=O)C)O[C@H](O[C@H]2C)C[C@](C)([C@H]2O)OC)[C@H]([C@](O)(C[C@H](C([C@@H]([C@H]1O)C)=O)C)C)O[C@H](O[C@@H]3C)[C@@H]([C@H](C3)N(C)C)O.OC(C[C@H](N)C(O)=O)=O
Clinical Information
– Launched
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial;DNA/RNA Synthesis
Isoform
– Macrolide
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
