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EPZ031686
$180 – $2,520
Products Details
Product Description
– EPZ031686 is an potent and orally active SMYD3 inhibitor and with an IC50 value of 3 nM. EPZ031686 can be used for cancer research[1].
Web ID
– HY-19324
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H34ClF3N4O4S
References
– [1]Mitchell LH, et, al. Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor. ACS Med Chem Lett. 2015 Aug 27;7(2):134-8.
CAS Number
– 2095161-11-6
Molecular Weight
– 591.09
Compound Purity
– 99.82
SMILES
– O=C(C1)NC2=C1C=C(C(N[C@@H]3C[C@H]4N(S(CC5CCN(CCCC(F)(F)F)CC5)(=O)=O)[C@H](CC4)C3)=O)C(Cl)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 35 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Histone Methyltransferase
Isoform
– SMYD3
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
