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Epiblastin A
$60 – $340
Products Details
Product Description
– Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1[1].
Web ID
– HY-114858
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C12H10ClN7
References
– [1]Andrei Ursu, et al. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol. 2016 Apr 21;23(4):494-507.
CAS Number
– 16470-02-3
Molecular Weight
– 287.71
Compound Purity
– 99.51
SMILES
– NC1=NC(N)=C2N=C(C(N)=NC2=N1)C3=CC=CC(Cl)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 4.55 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Casein Kinase
Pathway
– Cell Cycle/DNA Damage;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
