Download Files:
EP4 receptor antagonist 1
Price range: 171 CAD through 661 CAD
Products Details
Product Description
– EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 μM) against human EP1, EP2, and EP3 receptors.
Web ID
– T11211
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H21F3N4O3
References
– Yang JJ, et al. Discovery and Characterization of 1H-1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy. J Med Chem. 2020 Jan 23;63(2):569-590.
CAS Number
– 2287259-07-6
Molecular Weight
– C23H21F3N4O3
Compound Purity
– 0.9953
SMILES
– CC=Cc1nnn(Cc2ccc(cc2)C(F)(F)F)c1C(=O)N[C@@H](C)c1ccc(cc1)C(O)=O
Target
– P2X Receptor
Pathway
– GPCR/G Protein|||Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
