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Ensartinib hydrochloride
Price range: 96 CAD through 1,579 CAD
Products Details
Product Description
– Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.
Web ID
– T22324
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H29Cl4FN6O3
References
– Li T, et al. Chin Clin Oncol. 2019, 8(S1):S
CAS Number
– 2137030-98-7
Molecular Weight
– C26H29Cl4FN6O3
Compound Purity
– 0.9929
SMILES
– Cl.Cl.C[C@@H](Oc1cc(nnc1N)C(=O)Nc1ccc(cc1)C(=O)N1C[C@H](C)N[C@H](C)C1)c1c(Cl)ccc(F)c1Cl
Target
– c-Myc
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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