Ensartinib

SKU T37585-1 mg Category Brand:

Price range: 512 CAD through 4,960 CAD

Products Details

Product Description

– Ensartinib (X-396) is a potent and orally active dual ALK/MET inhibitor for the treatment of ALK-positive non-small cell lung cancer (NSCLC).

Web ID

– T37585

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H27Cl2FN6O3

Citations

– 1. Wu W, Li J, Yin Y, et al.Rutin attenuates ensartinib-induced hepatotoxicity by non-transcriptional regulation of TXNIP.Cell Biology and Toxicology.2024, 40(1): 38.

References

– Lovly CM, et al. Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinaseinhibitors. Cancer Res. 2011 Jul 15;71(14):4920-31.

CAS Number

– 1370651-20-9

Molecular Weight

– C26H27Cl2FN6O3

Compound Purity

– 0.9992

SMILES

– C(=O)(N1C[C@@H](C)N[C@@H](C)C1)C2=CC=C(NC(=O)C3=CC(O[C@H](C)C4=C(Cl)C(F)=CC=C4Cl)=C(N)N=N3)C=C2

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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