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EN450
Price range: 62 CAD through 2,192 CAD
Products Details
Product Description
– EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be used to study leukemia.
Web ID
– T77525
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H13ClN2O3S
References
– King EA, et al. Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB. Cell Chem Biol. 2023 Apr 20;30(4):394-402.e9.
CAS Number
– 793719-01-4
Molecular Weight
– C11H13ClN2O3S
Compound Purity
– 0.9972
SMILES
– O=C(C=C)NC1=CC(=CC=C1Cl)S(=O)(=O)N(C)C
Pathway
– NF-κB
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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