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EMT inhibitor-2
$400 – $3,400
Products Details
Product Description
– EMT inhibitor-2 (Compound 1) inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes. EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively[1].
Web ID
– HY-128859
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C24H26N2O8
References
– [1]Youn, Byung Soo, et al. Substituted chromenes for treatment of fibrosis or non-alcoholic steatohepatitis. US10370364.
CAS Number
– 2232228-60-1
Molecular Weight
– 470.47
Compound Purity
– 99.55
SMILES
– COC1=C(O)C2=C(OC(C3=CC=C(OC)C(OC)=C3)=CC2=O)C=C1OCCN(C4)CCNC4=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 83.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Cytochrome P450
Isoform
– CYP2;CYP3
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
