EML4-ALK kinase inhibitor 1
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EML4-ALK kinase inhibitor 1

SKU T11184-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 141 CAD through 3,152 CAD

Products Details

Product Description

– EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.

Web ID

– T11184

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H48N8O3

References

– Iikubo K, et al. Synthesis and structure-activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1683-1692.

CAS Number

– 1373409-08-5

Molecular Weight

– C31H48N8O3

Compound Purity

– 0.9914

SMILES

– CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1N[C@H]1CC[C@@H](CC1)OC

Target

– Others

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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