Elesclomol
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Elesclomol

SKU T6170-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 389 CAD

Products Details

Product Description

– Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-mediated Fe-S cluster biosynthesis.

Web ID

– T6170

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H20N4O2S2

Citations

– 1. Wu Z, Lin C, Zhang F, et al.TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal Cancer.Cancers.2023, 15(8): 2286. 2. Luo Y, Luo X, Ru Y, et al.Copper (II)-Based Nano-regulator Correlates Cuproptosis burst and Sequential Immunogenic Cell Death for Synergistic Cancer Immunotherapy.Biomaterials Research.. 3. Zhao Z, Miao Z, Hou Y, et al.A novel signature constructed by cuproptosis-related RNA methylation regulators suggesting downregulation of YTHDC2 may induce cuproptosis resistance in colorectal cancer.International Immunopharmacology.2024, 139: 112691. 4. Zhou Z, Dong D, Yuan Y, et al.Single cell atlas reveals multilayered metabolic heterogeneity across tumour types.EBioMedicine.2024, 109. 5. Qi R Q, Chen Y F, Cheng J, et al.Elabela alleviates cuproptosis and vascular calcification in vitaminD3-overloaded mice via regulation of the PPAR-γ/FDX1 signaling.Molecular Medicine.2024, 30: 223. 6. Luo X, Linghu M, Zhou X, et al.Merestinib inhibits cuproptosis by targeting NRF2 to alleviate acute liver injury.Free Radical Biology and Medicine.2025

References

– Bair JS, et al. Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death. J Am Chem Soc. 2010 Apr 21;132(15):5469-78.

CAS Number

– 488832-69-5

Molecular Weight

– C19H20N4O2S2

Compound Purity

– 0.9951

SMILES

– CN(NC(=O)CC(=O)NN(C)C(=S)c1ccccc1)C(=S)c1ccccc1

Pathway

– Apoptosis|||Metabolism|||Cytoskeletal Signaling|||Immunology/Inflammation|||NF-κB

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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