EIPA

SKU TQ0157-1 mL * 10 mM (in DMSO) Category Brand:

78 CAD

Products Details

Product Description

– EIPA (L593754) is a TRPP3 channel inhibitor (IC50=10.5 μM) and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy, and can be used in inflammation and tumor studies.

Web ID

– TQ0157

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C11H18ClN7O

Citations

– 1. Wang C, Hu R, Wang T, et al.A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A.Journal of Biological Chemistry.2023: 104605. 2. Chen L, Xu C, Xu H, et al.RVG29-modified oncolytic herpes simplex virus for intracranial tumor treatment.Nano Today.2025, 61: 102573.

References

– Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85.

CAS Number

– 1154-25-2

Molecular Weight

– C11H18ClN7O

Compound Purity

– 0.9997

SMILES

– CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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