EGFR-IN-9
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EGFR-IN-9

SKU T11163-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 846 CAD

Products Details

Product Description

– EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity.

Web ID

– T11163

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H24N4O3

References

– Coumar MS, et al. Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor leadidentification. J Med Chem. 2010 Jul 8;53(13):4980-8.

CAS Number

– 1226549-39-8

Molecular Weight

– C29H24N4O3

Compound Purity

– 0.998

SMILES

– OC[C@@H](Nc1ncnc2oc(c(-c3cccc(NC(=O)C=C)c3)c12)-c1ccccc1)c1ccccc1

Target

– Apoptosis|||Nucleoside Antimetabolite/Analog|||Autophagy

Pathway

– JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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