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EGFR/HER2-IN-9
$90 – $2,100
Products Details
Product Description
– EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor with IC50s of 3.2, 8.3 and 14 nM against EGFR, EGFR T790M and HER2, respectively[1].
Web ID
– HY-153111
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C25H25ClFN5O4
References
– [1]Yingjun Zhang, et al. Amino quinazoline derivatives as well as salts and application method thereof. Patent CN104119350A.
CAS Number
– 1637253-79-2
Molecular Weight
– 513.95
Compound Purity
– 98.73
SMILES
– COC(C(NC(/C=C/CN1C[C@@]2([H])[C@@](OCCO2)([H])C1)=O)=C3)=CC4=C3C(NC5=CC(Cl)=C(C=C5)F)=NC=N4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Isoform
– EGFR/ErbB1/HER1;ErbB2/HER2
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
