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Products Details
Product Description
– EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual inhibitor of EGFR and HER2[1].
Web ID
– HY-115952
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H23N5O3
References
– [1]Sangande, et al. 2-substituted 4-aminoquinazoline derivatives as potential dual inhibitors of EGFR and HER2: an in silico and in vitro study. Medicinal Chemistry Research 31.5 (2022): 762-771.
CAS Number
– 1031620-09-3
Molecular Weight
– 453.49
SMILES
– CC1=CC=C(C2=NN=C(C3=NC(NCC4=CC=C(OC)C=C4OC)=C5C=CC=CC5=N3)O2)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Isoform
– EGFR/ErbB1/HER1;ErbB2/HER2
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
