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EGFR/HER2/DHFR-IN-3

SKU T82492-5 mg Category Brand:

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Product Description

– EGFR/HER2/DHFR-IN-3 (compound 4c) is an efficacious dual inhibitor of EGFR/HER2 with IC50 values of 0.138 μM for EGFR and 0.092 μM for HER2, respectively, and also inhibits DHFR with an IC50 of 0.193 μM. It induces cell cycle arrest in the S phase and triggers apoptosis in MCF7 breast cancer cells [1].

Web ID

– T82492

Storage Temperature

– -20℃

Shipping

– Blue Ice

Pathway

– JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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