– EGCG-4″-sulfate, a predominant polyphenol in green tea, demonstrates notable anticancer, antioxidant, and anti-inflammatory effects, particularly against colorectal cancer, myeloid leukemia, and thyroid carcinoma [1] [2] [3] [4]. This compound not only inhibits cell proliferation and triggers cell apoptosis but also suppresses the activity of glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2), highlighting its important role in cancer prevention and treatment.