EG01377
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EG01377

SKU T11154-25 mg Category Brand:

Price range: 3,152 CAD through 5,440 CAD

Products Details

Product Description

– EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.

Web ID

– T11154

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H30N6O6S2

References

– Powell J, et al. Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells. J Med Chem. 2018 May 10;61(9):4135-4154.

CAS Number

– 2227996-00-9

Molecular Weight

– C26H30N6O6S2

SMILES

– S(NC1=C(C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)SC=C1)(=O)(=O)C2=C3C(=CC(=C2)C4=CC=C(CN)C=C4)CCO3

Target

– ADC Linker

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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