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Edasalonexent
$350 – $2,250
Products Details
Product Description
– Edasalonexent (CAT-1004) is an orally bioavailable NF-κB inhibitor.
Web ID
– HY-17630
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C31H42N2O3
References
– [1]Hammers DW, et al. Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle. JCI Insight. 2016 Dec 22;1(21):e90341.|[2]Donovan JM, et al. A Novel NF-κB Inhibitor, Edasalonexent (CAT-1004), in Development as a Disease-Modifying Treatment for Patients With Duchenne Muscular Dystrophy: Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics in Adult Subjects. J Clin Pharmacol. 2017 May;57(5):627-639.
CAS Number
– 1204317-86-1
Molecular Weight
– 490.68
Compound Purity
– 98.0
SMILES
– O=C(NCCNC(CC/C=CC/C=CC/C=CC/C=CC/C=CC/C=CCC)=O)C1=CC=CC=C1O
Clinical Information
– Phase 3
Research Area
– Metabolic Disease
Solubility
– DMSO : 120 mg/mL (ultrasonic)
Target
– NF-κB
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
