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Eckol

Products Details

Product Description

– Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC50s of 7.20 and 83.44 μM, respectively. Eckol shows stimulatory effects in maize and can be used as a plant biostimulant. Eckol also shows antiallergic and antiviral effects[1][2][3][4].

Web ID

– HY-114203

Shipping

– Room temperature

Molecular Formula

– C18H12O9

References

– [1]Jung HA, et al. Evaluation of the inhibitory effects of eckol and dieckol isolated from edible brown alga Eisenia bicyclis on human monoamine oxidases A and B. Arch Pharm Res. 2017 Apr;40(4):480-491.|[2]Rengasamy KR, et al. Enhancing growth, phytochemical constituents and aphid resistance capacity in cabbage with foliar application of eckol–a biologically active phenolic molecule from brown seaweed. N Biotechnol. 2016 Mar 25;33(2):273-9.|[3]Han EJ, et al. Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice. Nutrients. 2020 May 9;12(5):1361.|[4]Besednova NN, et al. Antiviral Effects of Polyphenols from Marine Algae. Biomedicines. 2021 Feb 17;9(2):200.

CAS Number

– 88798-74-7

Molecular Weight

– 372.28

SMILES

– OC1=C2C(OC3=C(O)C=C(O)C=C3O2)=C(OC4=CC(O)=CC(O)=C4)C(O)=C1

Clinical Information

– No Development Reported

Research Area

– Infection; Inflammation/Immunology; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Influenza Virus;Monoamine Oxidase

Isoform

– MAO-A;MAO-B

Pathway

– Anti-infection;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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