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Product Description
– Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC50s of 7.20 and 83.44 μM, respectively. Eckol shows stimulatory effects in maize and can be used as a plant biostimulant. Eckol also shows antiallergic and antiviral effects[1][2][3][4].
Web ID
– HY-114203
Shipping
– Room temperature
Molecular Formula
– C18H12O9
References
– [1]Jung HA, et al. Evaluation of the inhibitory effects of eckol and dieckol isolated from edible brown alga Eisenia bicyclis on human monoamine oxidases A and B. Arch Pharm Res. 2017 Apr;40(4):480-491.|[2]Rengasamy KR, et al. Enhancing growth, phytochemical constituents and aphid resistance capacity in cabbage with foliar application of eckol–a biologically active phenolic molecule from brown seaweed. N Biotechnol. 2016 Mar 25;33(2):273-9.|[3]Han EJ, et al. Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice. Nutrients. 2020 May 9;12(5):1361.|[4]Besednova NN, et al. Antiviral Effects of Polyphenols from Marine Algae. Biomedicines. 2021 Feb 17;9(2):200.
CAS Number
– 88798-74-7
Molecular Weight
– 372.28
SMILES
– OC1=C2C(OC3=C(O)C=C(O)C=C3O2)=C(OC4=CC(O)=CC(O)=C4)C(O)=C1
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Influenza Virus;Monoamine Oxidase
Isoform
– MAO-A;MAO-B
Pathway
– Anti-infection;Neuronal Signaling
Product type
– Natural Products
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