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Products Details
Product Description
– EBL-3183, an indole-2-carboxylate, is a potent metallo-β-lactamase (MBL) inhibitor. EBL-3183 is reversibly binding, non-covalent, competitive NDM-1 inhibitor with a pIC50 of 7.7[1].
Web ID
– HY-149929
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H27FN4O6S
References
– [1]Jürgen Brem, et al. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors. Nat Chem. 2022 Jan;14(1):15-24.
Molecular Weight
– 530.57
SMILES
– C[C@H](N1C[C@]2(OC1=O)C[C@@H](C2)CN)C3=CC=CC4=C3NC(C(O)=O)=C4C5=CC=C(C(F)=C5)NS(C)(=O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
