EB1
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EB1

SKU T73582-1 g Category Brand:

Price range: 109 CAD through 5,584 CAD

Products Details

Product Description

– EB1 is a potent and selective MNK kinase inhibitor with inhibitory effects on MNK1 and MNK2 with IC50 values of 0.69 μM and 9.4 μM, respectively.EB1 inhibits the growth of cancer cells, promotes apoptosis, and inhibits the phosphorylation of eIF4E.

Web ID

– T73582

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H14N4

References

– Aboukhatwa SM, et al. Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition. Bioorg Chem. 2022 Dec;129:106126.

CAS Number

– 42951-68-8

Molecular Weight

– C18H14N4

Compound Purity

– 0.9982

SMILES

– NC=1C2=C(C=C(N=C2NN1)C3=CC=CC=C3)C4=CC=CC=C4

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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