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Products Details
Product Description
– EB-0176 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.6439 and 0.0011 μM, respectively. EB-0176 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0176 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses[1].
Web ID
– HY-145275
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C23H33N5O7
References
– [1]Karade SS, et al. N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum α-Glucosidases I and II with Antiviral Activity. J Med Chem. 2021;64(24):18010-18024.
CAS Number
– 2758314-64-4
Molecular Weight
– 491.54
SMILES
– O[C@@H]1[C@H]([C@@H]([C@](O)(C[C@@H]1NCCCCCCNC2=C(C=C(C=C2)C3=NC=CC=N3)[N+]([O-])=O)CO)O)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
