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E7766 (diammonium salt)
$580 – $2,650
Products Details
Product Description
– E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. E7766 diammonium salt shows potent pan-genotypic and antitumor activities[1].
Web ID
– HY-111999A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H32F2N12O8P2S2
References
– [1]Dae-Shik Kim, et al. E7766, a Macrocycle-Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan-Genotypic Activity. ChemMedChem. 2021 Jun 7;16(11):1740-1743.
CAS Number
– 2242635-03-4
Molecular Weight
– 780.66
Compound Purity
– 99.73
SMILES
– F[C@@H]1[C@H](O[P@]2(S)=O)[C@@H](CO[P@]3(S)=O)O[C@H]1[N@]4C5=NC=NC(NC/C=C/CNC6=C(N=C[N@]7[C@@H]8O[C@H](CO2)[C@@H](O3)[C@H]8F)C7=NC=N6)=C5N=C4.N.N
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– H2O : 45 mg/mL (ultrasonic)
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
