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E6446 dihydrochloride
Price range: 174 CAD through 2,752 CAD
Products Details
Product Description
– E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.
Web ID
– T4068
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H37Cl2N3O3
References
– Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40.
CAS Number
– 1345675-25-3
Molecular Weight
– C27H37Cl2N3O3
Compound Purity
– 0.9944
SMILES
– Cl.Cl.C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1
Pathway
– Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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