(E/Z)-GO289

SKU T9356-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 1,226 CAD

Products Details

Product Description

– (E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.

Web ID

– T9356

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H15BrN4O2S

References

– Oshima T, et al. Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth. Sci Adv. 2019;5(1):eaau9060. Published 2019 Jan 23.

CAS Number

– 694522-87-7

Molecular Weight

– C17H15BrN4O2S

Compound Purity

– 0.9968

SMILES

– COc1cc(C=Nn2c(SC)nnc2-c2ccccc2)c(Br)cc1O

Pathway

– Metabolism|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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