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(E)-[6]-Dehydroparadol
$108 – $1,176
Products Details
Product Description
– (E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells[1][2].
Web ID
– HY-77293
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C17H24O3
References
– [1]Chen H, et, al. Metabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human. Mol Nutr Food Res. 2013 May;57(5):865-76.|[2]Zhu Y, et, al. Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators. Free Radic Biol Med. 2016 Jun;95:243-54.
CAS Number
– 878006-06-5
Molecular Weight
– 276.37
Compound Purity
– 95.0
SMILES
– CCCCCCCC(/C=C/C1=CC=C(O)C(OC)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 140 mg/mL
Target
– Apoptosis;Keap1-Nrf2
Pathway
– Apoptosis;NF-κB
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
