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DY-46-2
$450 – $1,480
Products Details
Product Description
– DY-46-2 is a high potency and selectivity novel non-nucleoside DNA methyltransferase 3A (DNMT3A) inhibitor with an IC50 value of 0.39 μM[1].
Web ID
– HY-151136
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H22N6O5S
References
– [1]J. Yu, et al. Discovery of novel non-nucleoside inhibitors with high potency andselectivity for DNA methyltransferase 3A. European Journal of Medicinal Chemistry (2022).
CAS Number
– 1105110-83-5
Molecular Weight
– 446.48
Compound Purity
– 99.12
SMILES
– O=C(C1=C(C)OC(N=CN2CCN3CCCC3)=C1C2=O)NC4=CC=C(S(=O)(N)=O)N=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– DNA Methyltransferase
Isoform
– DNMT3
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.