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Products Details
Product Description
– Dvd-445 has good anti-cancer effect.Dvd-445 is an effective peptide covalent thioredoxin reductase 1 (TrxR1) inhibitor with IC50 value of 0.60 mol/L M.
Web ID
– T11130
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H28F2N2O4
References
– Jovanović M, et al. Novel electrophilic amides amenable by the Ugi reaction perturb thioredoxin system via thioredoxin reductase 1 (TrxR1) inhibition: Identification of DVD-445 as a new lead compound for anticancer therapy. Eur J Med Chem. 2019 Aug 1;181:111580.
CAS Number
– 2375846-41-4
Molecular Weight
– C25H28F2N2O4
SMILES
– CN(CCOC(=O)C=CC(=O)c1ccc(F)cc1)C(C(=O)NC(C)(C)C)c1ccc(F)cc1
Target
– NF-κB
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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