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Products Details
Product Description
– Durvalumab (MEDI 4736) is a humanized monoclonal antibody targeting PD-L1. It can block the interaction of PD-L1 with PD-1 and CD80, with IC50 values of 0.1 and 0.04 nM, respectively. Durvalumab is often used in combination with platinum-based compounds for the treatment of non-small cell lung cancer and advanced hepatocellular carcinoma cells.
Web ID
– T11126
Storage Temperature
– -20℃
Shipping
– Blue Ice
References
– Faiena I, et al. Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. Drug Des Devel Ther. 2018 Jan 23;12:209-215.
CAS Number
– 1428935-60-7
Molecular Weight
Compound Purity
– 97.2% (SDS-PAGE); 95.3% (SEC-HPLC)
Target
– ADC Linker
Pathway
– Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis
Product type
– Inhibitory Antibodies
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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