Durvalumab

SKU T11126-1 mg Category Brand:

Price range: 365 CAD through 3,408 CAD

Products Details

Product Description

– Durvalumab (MEDI 4736) is a humanized monoclonal antibody targeting PD-L1. It can block the interaction of PD-L1 with PD-1 and CD80, with IC50 values of 0.1 and 0.04 nM, respectively. Durvalumab is often used in combination with platinum-based compounds for the treatment of non-small cell lung cancer and advanced hepatocellular carcinoma cells.

Web ID

– T11126

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Faiena I, et al. Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. Drug Des Devel Ther. 2018 Jan 23;12:209-215.

CAS Number

– 1428935-60-7

Molecular Weight

Compound Purity

– 97.2% (SDS-PAGE); 95.3% (SEC-HPLC)

Target

– ADC Linker

Pathway

– Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis

Product type

– Inhibitory Antibodies

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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