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Dual FAAH/sEH-IN-1
SKU
HY-144738-1mg
Category Reference compound
Tags Epoxide Hydrolase;FAAH, Inflammation/Immunology, Metabolic Enzyme/Protease;Neuronal Signaling
$567 – $1,700
Products Details
Product Description
– Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].
Web ID
– HY-144738
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H22ClN3O3S2
References
– [1]Wilt S, Kodani S, Valencia L, et al. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021;51:116507.
CAS Number
– 2756099-59-7
Molecular Weight
– 512.04
SMILES
– O=C(C1CCN(CC1)S(=O)(C2=CC=CC=C2Cl)=O)NC3=CC=C(C=C3)C4=NC5=CC=CC=C5S4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Epoxide Hydrolase;FAAH
Pathway
– Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.