DRP1i27

SKU HY-152086-1 mg Category Tags , ,

$190$4,800

Products Details

Product Description

– DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury[1].

Web ID

– HY-152086

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture and light)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C20H26N6O

References

– [1]Rosdah AA, et al. A novel small molecule inhibitor of human Drp1. Sci Rep. 2022 Dec 13;12(1):21531.

CAS Number

– 1453028-33-5

Molecular Weight

– 366.46

Compound Purity

– 98.73

SMILES

– CC1=C(NC=N1)CN2C[C@@H]3CC[C@@H](N(C3)CC4=CC=C(O4)C5=NNC=C5)C2

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Dynamin

Pathway

– Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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