DRI-C21045

SKU T11096-5 mg Category Brand:

Price range: 69 CAD through 843 CAD

Products Details

Product Description

– Dri-c21045 showed concentration-dependent inhibition of NF-kB activation and all CD40L induced by B cell proliferation with IC50 of 17.1 μM and 4.5 μM, respectively. Dri-c21045 is an effective selective inhibitor of CD40-CD40L synergistic stimulator protein-protein interaction (PPI) with IC50 of 0.17 μM.

Web ID

– T11096

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H24N2O7S

References

– Chen J, et al. Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction. J Med Chem. 2017 Nov 9;60(21):8906-8922.

CAS Number

– 2101765-81-3

Molecular Weight

– C32H24N2O7S

Compound Purity

– 0.981

SMILES

– COC(=O)c1ccc(cc1)C(=O)Nc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc2cccc(c12)S(O)(=O)=O

Target

– MAO

Pathway

– NF-κB

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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