Download Files:
Doxazosin (mesylate)
$77 – $99
Products Details
Product Description
– Doxazosin mesylate (UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.
Web ID
– HY-B0098A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H29N5O8S
References
– [1]Sun, J.A., et al., Stereoselective binding of doxazosin enantiomers to plasma proteins from rats, dogs and humans in vitro. Acta Pharmacol Sin, 2013. 34(12): p. 1568-74.|[2]D’Eletto, R.D. and N.B. Javitt, Effect of doxazosin on cholesterol synthesis in cell culture. J Cardiovasc Pharmacol, 1989. 13 Suppl 2: p. S1-4; discussion S4.|[3]Miura, Y. and K. Yoshinaga, Doxazosin: a newly developed, selective alpha 1-inhibitor in the management of patients with pheochromocytoma. Am Heart J, 1988. 116(6 Pt 2): p. 1785-9.
CAS Number
– 77883-43-3
Molecular Weight
– 547.58
Compound Purity
– 98.34
SMILES
– O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OC5=CC=CC=C5OC4.CS(=O)(O)=O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Endocrinology; Cancer
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic)
Target
– Adrenergic Receptor;Autophagy;Mitophagy
Isoform
– α adrenergic receptor
Pathway
– Autophagy;GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
