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Products Details
Product Description
– Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor-selective or multitarget bitopic ligand (Ki = 1.58 nM) potentially useful for central nervous system disorders.
Web ID
– HY-139680
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C31H35Cl2N3O3
References
– [1]Bonifazi A, et al. Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders. ACS Chem Neurosci. 2021 Oct 6;12(19):3638-3649.
Molecular Weight
– 568.53
SMILES
– O=C(NCCCCN1CCN(C2=CC=CC(Cl)=C2Cl)CC1)C3OCC(C4=CC=CC=C4)(C5=CC=CC=C5)OC3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Isoform
– D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
