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DNA-PK-IN-9
SKU
HY-146566-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR, DNA-PK
Products Details
Product Description
– DNA-PK-IN-9 (compound YK6) is a potent DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 value of 10.47 nM. DNA-PK-IN-9 can be used for researching anticancer[1].
Web ID
– HY-146566
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H21N5O2
References
– [1]Ding Z, et al. Discovery of novel 7,8-dihydropteridine-6(5H)-one-based DNA-PK inhibitors as potential anticancer agents via scaffold hopping strategy. Eur J Med Chem. 2022;237:114401.
Molecular Weight
– 375.42
SMILES
– CC1=CC2=C(C=C1NC3=NC=C4C(C5(C(N4C)=O)CCOCC5)=N3)C=CC=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA-PK
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.