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Products Details
Product Description
– DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of <30 nM for both TBK1 and IKKε[1].
Web ID
– HY-148206
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H17FN8
References
– [1]Gary Karl Newton, et al. Pyrimidine compounds useful in the treatment of diseases mediated by ikke and/or tbk1 mechanisms. Patent WO2014128486A1.
CAS Number
– 1623123-95-4
Molecular Weight
– 376.39
SMILES
– N#CC1=C(N2CC[C@@H](C2)F)N=CC(C3=NC(NC4=CN=C(N)C=C4)=NC=C3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IKK
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
