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DMPQ (dihydrochloride)
Products Details
Product Description
– DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC50 of 80 nM[1].
Web ID
– HY-108627
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H16Cl2N2O2
References
– [1]Dolle RE, et al. 5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 1994 Aug 19;37(17):2627-9.
CAS Number
– 1123491-15-5
Molecular Weight
– 339.22
SMILES
– COC1=CC(OC)=C2C=C(C3=CC=NC=C3)C=NC2=C1.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– PDGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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