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DMP 777

SKU HY-75957-10 mg Category Reference compound Tags Elastase, Inflammation/Immunology, Metabolic Enzyme/Protease

$200 – $1,350

Size10 mg

5 mg 10mM/1mL 10 mg 25 mg 50 mg 100 mg

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$300

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Products Details

Product Description

– DMP 777 is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.

Web ID

– HY-75957

Storage Temperature

– -20°C (Powder, stored under nitrogen)

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C31H40N4O6

References

– [1]Weis VG, et al. Maturity and age influence chief cell ability to transdifferentiate into metaplasia. Am J Physiol Gastrointest Liver Physiol. 2016 Nov 23:ajpgi.00326.2016|[2]Zagrobelny J, et al. Separation of the four stereoisomers of a potent inhibitor (L-694,458) of human leukocyte elastase and its determination in human plasma using achiral/chiral chromatography with column switching. J Pharm Biomed Anal. 1998 Sep 1;17(6-7|[3]Ogawa M, et al. Omeprazole treatment ameliorates oxyntic atrophy induced by DMP-777. Dig Dis Sci. 2006 Mar;51(3):431-9.

CAS Number

– 157341-41-8

Molecular Weight

– 564.67

Compound Purity

– 99.75

SMILES

– CCC[C@H](C1=CC2=C(C=C1)OCO2)NC(N3[C@H](C(CC)(C3=O)CC)OC4=CC=C(C=C4)C(N5CCN(CC5)C)=O)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 38.33 mg/mL (ultrasonic)

Target

– Elastase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.