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Disitamab vedotin

SKU T39595-1 mg Category Brand:

Price range: 555 CAD through 3,712 CAD

Products Details

Product Description

– Disitamab vedotin (RC-48) is a newly developed antibody-active molecule conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2), consisting of hertuzumab coupled to monomethyl auristatin E (MMAE) via a cleavable linker. Disitamab vedotin showed anti-tumor and anti-proliferative activities in gastric cancer cells with different HER-2 expression levels and inhibited the expression of HER-2 protein in gastric cancer cells.

Web ID

– T39595

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Deeks ED. Disitamab Vedotin: First Approval. Drugs. 2021;81(16):1929-1935.

CAS Number

– 2136633-23-1

Molecular Weight

Compound Purity

– 0.98

Pathway

– Angiogenesis|||Antibody-drug Conjugate/ADC Related|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Inhibitory Antibodies

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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