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Diprovocim-X
$720 – $5,760
Products Details
Product Description
– Diprovocim-X (compound 35) is a potent TLR1/TLR2 (toll-like receptor 1/2) agonist, with EC50 values of 0.14 and 0.75 nM for hTLR1/TLR2 and mTLR1/TLR2, respectively. Diprovocim-X is a potent adjuvant in vivo in mice, and serves to stimulate the adaptive immune response[1].
Web ID
– HY-150501
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C66H83N7O10
References
– [1]Yang MH, et al. Next-Generation Diprovocims with Potent Human and Murine TLR1/TLR2 Agonist Activity That Activate the Innate and Adaptive Immune Response. J Med Chem. 2022 Jun 29.
Molecular Weight
– 1134.41
Compound Purity
– 98.64
SMILES
– O=C(OCCCCCCCCCCCCNC([C@@H]1CN(C(C2=CC=C(C(N3C[C@@H](C(N[C@@H]4[C@@H](C5=CC=CC=C5)C4)=O)[C@H](C(N[C@@H]6[C@@H](C7=CC=CC=C7)C6)=O)C3)=O)C=C2)=O)C[C@H]1C(N[C@@H]8[C@@H](C9=CC=CC=C9)C8)=O)=O)CNC(OC(C)(C)C)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Toll-like Receptor (TLR)
Isoform
– TLR1;TLR2
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
