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Dimaprit (dihydrochloride)
$60 – $160
Products Details
Product Description
– Dimaprit dihydrochloride is a selective histamine H2 receptor agonist, it also inhibits nNOS with an IC50 of 49 μM. Dimaprit dihydrochloride can stimulate gastric acid secretion[1][2].
Web ID
– HY-B1478
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C6H17Cl2N3S
References
– [1]Parsons ME, et, al. Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) – a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology. Agents Actions. 1977 Mar; 7(1): 31-7.|[2]Paquay JB, et, al. Nitric oxide synthase inhibition by dimaprit and dimaprit analogues. Br J Pharmacol. 1999 May; 127(2): 331-4.
CAS Number
– 23256-33-9
Molecular Weight
– 234.19
Compound Purity
– 98.70
SMILES
– NC(SCCCN(C)C)=N.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Histamine Receptor;NO Synthase
Isoform
– H2 Receptor;nNOS
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
