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Dihydrolipoic Acid
SKU
HY-116807-100 mg
Category Reference compound
Tags Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB, Inflammation/Immunology; Neurological Disease, Reactive Oxygen Species
$40 – $110
Products Details
Product Description
– Dihydrolipoic Acid (DHLA) is an excellent antioxidant capable of scavenging almost any oxygen-centered radical[1]. Dihydrolipoic acid exhibits anti-inflammatory properties in various diseases. Dihydrolipoic Acid exerts a preventive effect via ERK/Nrf2/HO-1/ROS/NLRP3 pathway in LPS-induced sickness behavior rats. Dihydrolipoic Acid can be used for the reaserch of depression[2].
Web ID
– HY-116807
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C8H16O2S2
References
– [1]Romina Castañeda-Arriaga, et al. Lipoic acid and dihydrolipoic acid. A comprehensive theoretical study of their antioxidant activity supported by available experimental kinetic data. J Chem Inf Model. 2014 Jun 23;54(6):1642-52.|[2]Hetao Bian, et al. Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat. J Neuroinflammation. 2020 May 25;17(1):166.
CAS Number
– 462-20-4
Molecular Weight
– 208.34
Compound Purity
– 98.57
SMILES
– OC(CCCCC(CCS)S)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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