(-)-Dihydroguaiaretic acid

$390

Only 1000 item(s) left in stock.

Products Details

Product Description

– (-)-Dihydroguaiaretic acid is a Lipoxygenase inhibitor that has antioxidant activity. (-)-Dihydroguaiaretic acid inhibits the oxidation of unsaturated fatty acids and removes free radicals. (-)-Dihydroguaiaretic acid also has anticancer activity with an IC50 value of 7.49 μM (A549 cells)[1][2].

Web ID

– HY-N10898

Storage Temperature

– -20°C (Powder, protect from light)

Shipping

– Blue Ice

Molecular Formula

– C20H26O4

References

– [1]Yamauchi S, et al. Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7′-oxodihydroguaiaretic acid. Biosci Biotechnol Biochem. 2008 Nov;72(11):2981-6. |[2]Davis R A, et al. Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum[J]. Bioorganic & medicinal chemistry, 2009, 17(3): 1387-1392.

CAS Number

– 124649-78-1

Molecular Weight

– 330.42

Compound Purity

– 98.79

SMILES

– COC(C=C1C[C@@H](C)[C@H](C)CC2=CC(OC)=C(C=C2)O)=C(C=C1)O

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Lipoxygenase

Pathway

– Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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