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Didesethyl chloroquine
SKU
HY-100662-10mM/1mL
Category Reference compound
Tags Cardiovascular Disease, Drug Metabolite, Metabolic Enzyme/Protease
$550 – $605
Products Details
Product Description
– Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial agent Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].
Web ID
– HY-100662
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C14H18ClN3
References
– [1]Biot C, et al. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg Med Chem. 1999 Dec;7(12):2843-7.|[2]Essien EE, et al. Effects of chloroquine and didesethylchloroquine on rabbit myocardium and mitochondria. J Pharm Pharmacol. 1986 Jul;38(7):543-6.
CAS Number
– 4298-14-0
Molecular Weight
– 263.77
Compound Purity
– 99.91
SMILES
– CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCN
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.