DI-591

SKU T11033-25 mg Category Brand:

Price range: 2,272 CAD through 4,752 CAD

Products Details

Product Description

– DI-591 is an effective, high-affinity and cell-permeability inhibitor for DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 and nM and 10.4 nM, respectively, and has no obvious binding to DCN3, DCN4 and DCN5 proteins.

Web ID

– T11033

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H47N5O4S

References

– Zhou H, et al. A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation. Nat Commun. 2017 Oct 27;8(1):1150.

CAS Number

– 2245887-38-9

Molecular Weight

– C31H47N5O4S

SMILES

– CCC(=O)N[C@@H](Cc1nc2ccc(cc2s1)C(C)C)C(=O)N[C@H](CNC(=O)CCN1CCOCC1)C1CCCCC1

Target

– PROTAC Linker

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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